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Abstract Background: COVID-19 is not a short-term acute health care problem that will go away and not return. Fatigue is a commonly reported symptom of Post-acute covid-19 which is a multisystem disease.Purpose: To determine the prevalence of fatigue in adult patients post mild and moderate covid-19 cases and to investigate its relationshipto dyspneaandother factors (age, sex, BMI, smoking status, Data about status of covid-19 if they were hospitalized or not hospitalizedandthe received treatment). Methods: Eighty-one post covid-19 patients from both genders were recruited fromthe registry records of preventive medicine and surveillance of Ministry of Health and Population in the governorate of El Minya/ Egypt. The Study was conducted from 15st September 2020 till 15st December 2020. Demographic data were collected (age, sex, BMI),smoking status, Data about status of covid-19 if they were hospitalized or not hospitalized and the received treatment. Fatigue was assessed by using the Modified Fatigue Impact Scale (MFIS).Shortness of breath (dyspnea) was evaluated by the Numerical rating scale of dyspnea(NRS). Results:The prevalence of fatigue in adult patients post mild and moderate covid-19 cases after three to five months from their recovery was 64.2% using the MFIS. There was nosignificant association between fatigue and age, sex, BMI, smoking,hospitalization and the received treatment. The correlation between NRS and MFIS was a significant moderate positive correlation (r = 0.39, p = 0.0001) |