الفهرس | Only 14 pages are availabe for public view |
Abstract The present study was carried out to evaluate the efficiency of camel’s milk to ameliorate the toxicity of aluminum chloride AlCl3 on some hematological parameters; hepatic, renal functions and lipids profile; as well as the histopathological alterations of some organs. Forty rats were divided into 5 treatment groups (8 rats in each group): Group1: Normal rats (negative control); Group2: AlCl3 induced toxicity (positive control); Group3: AlCl3 induced toxicity rats fed on raw camel milk; Group4: AlCl3 induced toxicity rats fed on heat treated camel milk; and Group5: AlCl3 induced toxicity rats fed on sweet acidophilus camel milk. Rats were treated by 5ml camel{u2019}s milk 10 min before the administration of 1 ml AlCl3; and had their respective doses daily for 30 successive days orally. AlCl3 oral administration resulted in a significant decrease in red blood cells count (RBC’s), significant increase in mean corpuscular volume (MCV) and mean corpuscular hemoglobin (MCH) in AlCl3 group compared to the control group (normal rats); while hemoglobin (Hb), hematocrit (Hct), mean corpuscular hemoglobin concentration (MCHC), platelets (plt), reticulocytes (Retics) did not revealed significant changes between the two groups the obtained anemia was macrocytic normochromic. The lipids profile; hepatic and renal functions showed non-significant changes between different groups; however, histopathological examination showed variable alterations of varying severity in different organs; as a response to AlCl3 and camel’s milk administration. Camel{u2019}s milk administration in groups 3, 4, 5 alleviated the toxic effect of AlCl3 with variable degrees between different groups |