الفهرس 
Impact of Premenstrual Syndrome on Multiple Sclerosis Symptoms in Adult Female
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Abstract
Background: Premenstrual syndrome (PMS) is a combination of symptoms that many women get about a week or two before their period. Most women, over 90%, got some premenstrual symptoms, such as bloating, headaches, and moodiness.Multiplesclerosis(MS)the most prevalent neurological disability, is an autoimmune-mediated disorder that affects the central nervous system (CNS) and often leads to severe physical or cognitive incapacitation as well as neurological problems in young adults.This study aimed to know the impact of premenstrual syndrome on multiple sclerosis symptoms.Subjects: Forty women having MS and complained from PMS, aged 20-35 years, with BMI less than 30 kg/m2, were selected randomly from Health Insurance Authority in El-Dokki.They were assessed during two periods (normal and premenstrual days). Material and Method:The MS symptoms was assessed through expanded disability status scale with functional system scale and fatigue severity scale also the premenstrual syndrome was diagnosed through tracking the symptoms by PMS Tracker and the intensity of symptoms was assessed by numerical pain scale. Results:Multiple pairwise comparison tests revealed that there was significant increase in expanded disability status scale with functional system score, fatigue severity scale as well as pain rating scale in premenstrual period compared to the normal days with (p=0.006, p=0.001 and p=0.001) respectively. Conclusion: Premenstrual syndrome had an effect on worsening the symptoms of multiple sclerosis