الفهرس 
Evaluation of the effect of sperms vacuolation on success rate of fertilization
Abstract EnglishOnly 14 pages are availabe for public view
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Abstract
The human sperms head vacuoles and their potential role in male infertility are still poorly understood.The aim of this study was to identify the clinical features of human sperms head vacuoles in men included in the in vitro fertilization programme: men with normal (normozoospermia) and impaired sperm morphology (teratozoospermia).The sperm samples were observed under 6600- time magnification using intracytoplasmic morphological selected sperm injection (IMSI).The proportion of sperm with head vacuoles was evaluated and related to the outcome of in vitro fertilization. The sperm of men with impaired sperm morphology was characterized by a higher proportion of fertilization rate. The sperm head vacuoles were related to impaired semen quality (sperm concentration, motility, and morphology) but were not influenced by male factors (semen volume, height, age, weight, or body mass index). Moreover, sperm head vacuoles were not related to impaired fertilization rate merely after classical in vitro fertilization (IVF).Our study was conducted on 100 patients undergoing IMSI cycles with poor prognosis; poor responder women, whose age is 27 or more, required 375 I.U. of gonadotropin or more per day to well stimulate their follicles. IMSI was performed for 100 semen sample patients were divided into two groups to their vacuolation percentage.There was no difference in the percentage of fertilization rate