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Abstract Background: Bariatric surgery has been shown in multiple studies to produce substantial durable weight loss and improve or cure many of the symptoms of metabolic syndrome including type II diabetes, hypertension, sleep apnea and hyperlipidemia. Single anastomosis duodeno-ileal bypass with sleeve gastrectomy (SADI-S) is a novel bariatric operation based on the principles of bilio-pancreatic diversion. The reason for developing a new technique or for modifying a pre-existing one was to simplify the procedure, to decrease the potential complication rate, and to maintain or even to improve, if possible, the out-comes of the original operation. Aim of the Work: To compare Single anastomosis Duodeno-Ileal Bypass with Sleeve Gastrectomy Versus Mini-Gastric-Bypass in treatment of type 2 Diabetes mellitus in obese patients. Patients and Methods: This prospective study was conducted on 50 patients with obesity type 2 and were operated with the same surgical team at Ain shams University Hospitals between June 2016 –June 2018 at Ain Shams University Hospitals, Cairo, Egypt. Results: Follow up of visits in out-patients clinic at 3, 6 and 12 months for measurement of: BMI, HbA1c and FBS, Lipid profile and follow up for changes in doses or type or discontinuation of anti-diabetic medications and anti-hypertensive medication. Complete resolution of diabetes occurred in 92 % in SADIS versus 80% in MGB operation. Conclusion: Metabolic surgery is a safe option for carefully selected patients with metabolic syndrome. The increased risk for type 2 diabetes and cardiovascular disease demands therapeutic attention for those at high risk. Our study suggests that both SADIS and MGB is highly effective in controlling Diabetes mellitus, Hypertension and Hyperlipidemia. |