الفهرس 
AbstractOnly 14 pages are availabe for public view
 |  | from | 151 |  |  |
| | | from | 151 | | |
Abstract
Different methods have been introduced for acceleration of orthodontic tooth movement. Platelet rich plasma (PRP) is one of the most recently used techniques because it is less invasive with minimal side effects. Aim : To evaluate the effect of submucosal injection of PRP on the rate of maxillary canine retraction for four months follow up period. Materials & Methods : Twenty patients were selected and randomly assigned in a split mouth trial designed to obtain PRP injection in one side (study side) while the other received no injection and served as a control. Injection was done distal to the canine before canine retraction and not repeated again. After extraction, leveling and alignment ; canine retraction was done on 0.017x0.025-inch stainless steel arch wire with closed coil spring from the canine hook to a mini-screw inserted between upper second premolar and first molar on both sides. The study duration was 4 months. Alginate impression was taken before canine retraction and every month for four months. Data were obtained monthly from digitized models in addition to pre and post retraction maxillary CBCT images. The primary outcome was the rate of canine retraction per month. The secondary outcomes were the effect of PRP injection on anchorage loss, canine tipping, canine rotation, root resorption, bone density. Pain assessment was carried out by visual analogue scale (VAS). Results : The canine retraction rate in the study side was faster than the control side with a statistically significant difference (P<0.05) in all the four months of the study duration. The total distance travelled by the canine was greater in the study side with a statistically significant difference (P=0.022). Insignificant differences were detected regarding anchorage loss, canine rotation and root resorption between both sides(p>0.05). Significant differences were detected regarding canine tipping and bone density between both sides(p<0.05). Higher pain levels were observed in the study side. Conclusion: Submucosal injection of PRP is a minimally invasive and safe approach for accelerating canine retraction and reducing overall treatment time.