الفهرس | Only 14 pages are availabe for public view |
Abstract from this work, it could be concluded that: Mean platelet volume is considered as a promising predictor of no-reflow phenomenon after primary PCI. Neutrophils to lymphocytes ratio has an important role in predicting no reflow phenomenon in patients undergoing PPCI. More Manipulation with Post stent dilatation is associated with no reflow phenomenon. Low ejection fraction is associated with patients who had NRP. RECOMMENDATIONS Large scale multicenter further studies are required to confirm the exact role of neutrophil and lymphocyte in the pathogenesis of no reflow phenomenon to permit early screening for prevention of this phenomenon. Future studies are needed to explore the risk and the benefits of post stent dilatation in STEMI patients after primary PCI to develop new strategies for screening and follow up of this serious complication. STUDY LIMITATIONS The study was included STEMI patients only in two hospitals. Small number of patients only 100 patients in our study. No long -term follow up to our patients. The absence of myocardial blush evaluation for microvascular flow. EF evaluation by M mode only no 2D evaluation. SUMMARY T his study was designed to investigate the role of neutrophil-to-lymphocyte ratio and mean platelet volume in predicting coronary no-reflow in patients with ST elevation myocardial infarction undergoing primary percutaneous coronary intervention. The patients were divided into 2 groups according to TIMI flow grades after primary PCI. 50 patients with TIMI flow grade 3 formed (reflow group) and 50 patients with TIMI flow grades 0-2 formed (no reflow group). The results of the present study showed the following: manipulation with post stent dilatation in no reflow group were significantly higher than in the reflow group (P = 0.028). EF by M mode was significantly lower in the no reflow group cases compared to those of reflow group (P = 0.040). Absolute lymphocytes were significantly higher in the no reflow group cases compared to those of reflow group (P = 0.001). Neutrophils to lymphocytes ratio were significantly higher in the no reflow group cases compared to those of reflow group (P = 0.011). MPV was significantly higher in the no reflow group cases compared to those of reflow group (P = 0.001). Hb level was significantly higher in the no reflow group cases compared to those of reflow group (P = 0.005). Mean platelet volume and Neutrophil to lymphocyte ratio are considered a promising positive predictors of no-reflow phenomenon after primary PCI. |