الفهرس | Only 14 pages are availabe for public view |
Abstract In this study, we aimed to determine role of Ultrasound in diagnosis of idiopathic pulmonary fibrosis. This cross-sectional study was conducted at tertiary care hospital at Ain Shams University hospitals from May 2021 till November 2021 and performed on total 20 patients diagnosed with idiopathic pulmonary fibrosis and had previous clinical features, documented high-resolution computed tomography (HRCT) scan findings and comparing it with lung ultrasound findings. During this study, 40 patients were assessed for eligibility and 40 patients were included in the study. Ultimately, the analysis was based on the data of 40 patients diagnosed with idiopathic pulmonary fibrosis and idiopathic interstitial pneumonia. Our study results revealed that B-lines number and Pleural lines thickness statistically were significantly higher in IPF group and Pleural lines interruption statistically was significantly frequent only in IPF group. Consequently, B-lines number and Pleural lines thickness statistically had significant high diagnostic performance in the diagnosis of IPF with cut-off of ≥3.0 which indicates that B-lines number ≥3.0 and Pleural lines thickness ≥3.0 mm had perfect sensitivity and LR+, while Pleural lines interruption had perfect specificity. B-lines number ≥3.0 had highest diagnostic accuracy, Youden’s index and kappa. Our research study revealed that B-lines number and Pleural lines thickness statistically were significantly higher in multiple zones spread cases (p value<0.001). Pleural lines interruption statistically was significantly more frequent in multiple zones spread cases. Consequently, B-lines number and Pleural lines thickness statistically had significant high diagnostic performance in the diagnosis of multiple zones spread with cut-off value of ≥5.0 which indicates that B-lines number ≥5.0 and Pleural lines thickness ≥5.0 mm had perfect sensitivity and LR+. B-lines number ≥5.0 had highest specificity, diagnostic accuracy, Youden’s index and kappa. |