الفهرس 
IntroductionOnly 14 pages are availabe for public view
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Abstract
Diabetic retinopathy is microvascular complication of diabetes mellitus and is the leading cause of blindness in working-age populations worldwide. Almost 30% of patients with diabetes mellitus complicated by diabetic retinopathy, and proliferative diabetic retinopathy (PDR) affects 9% of these, with consequent severe visual impairment.
Fluorescein angiography is a useful land important tool to confirm neovascularization by dye diffusion; however, the origin and the vessel structure of neovascularization cannot be identified by FA images, because they are limited to 2 dimensions, there are no segmentation data, and views are shielded by dye diffusion. Optical coherence tomography (OCT) is a noninvasive technique that provides cross-sectional retinal imaging and has been used clinically to diagnose and follow structural changes, such as macular edema, in diabetic retinopathy.
Optical coherence tomography angiography (OCTA) produces substantially improved detection of retinal blood vessels; it was developed for 2- and 3-dimensional noninvasive vascular mapping at the microcirculation level. The use of the split-spectrum amplitude-decorrelation angiography (SSADA) algorithm improved the signal-to-noise ratio of flow detection, allowing the detection and visualization of blood flow, the morphology of retinal vessels, and identification of ischemia with special emphasis on the retinal and papillary microvasculature on a layer-by-layer basis.
This study aimed to classify retinal neovascularization in untreated early stages of proliferative diabetic retinopathy (PDR) based on optical coherence tomography angiography (OCTA).
To elucidate our aim, this was cross sectional study was conducted on twenty-four eyes was undergo color fundus photography, fluorescein angiography (FA), and OCTA examinations who were diagnosed by the Department of Ophthalmology, Menoufia University, Menoufia, Egypt during the period from February 2021 to July 2021.