الفهرس 
الغلافيوجد فقط 14 صفحة متاحة للعرض العام
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المستخلص
Abstract
Searching for effective, low cost and less side effect containing herbal hypoglycemic agents is important therefore, the present study was performed to evaluate the effect of olive leaves, stevia leaves and flaxseed extracts on diabetic rats. A total of forty eight male healthy rats, weighing (201±5g) were classified into 3 main groups of extraction of olive leaves, stevia leaves and flaxseed each group was classified into 2 subgroups (levels of each type of extract at 0.2 and 0.5%); in addition to the control negative (-ve) and the control positive (+ve) groups. The extracts are taken orally. The rats were divided into eight groups: group (1), the control negative (-ve) was fed on the basal diet. group (2), the control positive (+ve) (diabetic rats) was fed on the basal diet. Groups (3 and 4) are diabetic rats fed on the basal diet containing olive leaves extract at 0.2 and 0.5%. Groups (5 and 6) are diabetic rats groups fed on the basal diet containing stevia leaves extract at 0.2 and 0.5%. Groups (7 and 8), are diabetic rats groups were fed on the basal diet containing flaxseed extract 0.2 and 0.5%.
At the end of the experimental period (6 weeks), rats were sacrificed and blood samples were collected to obtain serum. The results indicated that, STZ treated rats showed significant increase in glucose levels compared to normal rats. Supplementation with different levels of olive leaves, stevia leaves and flaxseed extracts in the diet caused significant decrease (P<0.05) in the concentration of glucose level compared to the positive control. It was also observed that the concentration of serum lipid profile, liver functions and kidney functions were significantly improved for all tested groups, compared to the positive control group. In conclusions, diet supplemented olive leaves, stevia leaves and flaxseed caused an improvement of the biochemical results from diabetes, therefore olive leaves, stevia leaves and flaxseed could be used as a suitable supplementation therapy for diabetic patients.
Keywords: Diabetes, olive leaves, stevia leaves, flaxseed, glucose.