الفهرس 
AminophosphonatesOnly 14 pages are availabe for public view
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Abstract
y
Organophosphorus compounds especially, α-aminophosphonic acids (I) and
their esters (II), have a potential biological activity due to the similarity with α-
amino acids (III). They represent an essential analogy to α-amino acids (III) as we
replaced a carboxylic group with a phosphonic acid ester moiety (cf. scheme. 1).
The development of efficient synthetic procedures to prepare new analogs are
urgently needed in the field of organophosphorus chemistry.
Scheme 1.Structures of α-aminophosphonic acids I, α-aminophosphonic esters
II, and α -amino acids III
In continuation of our previous work to improve synthesis and enhance the
scalability of organophosphorus compounds to be used in different biological
applications as antibacterial agents. In recent years metal-organic frameworks
(MOFs) received much attention from many researchers and have been employed
in numerous applications such as heterogeneous catalysts. This encourage us to
study the catalytic application of MOF in one-pot three components KabachnikFields reaction in synthesis of α-aminophosphonates .