الفهرس 
IntroductionOnly 14 pages are availabe for public view
 |  | from | 160 |  |  |
| | | from | 160 | | |
Abstract
Type 1 diabetes is one of the most common chronic childhood conditions and its incidence is rising worldwide among pre-school aged children. This condition is now mostly managed using flexible intensive insulin regimens, which involve multiple daily tasks (e.g. regular blood glucose monitoring, carbohydrate counting, calculating and administering insulin)
Well-designed disease registries integrate a variety of information, including patient demographics, laboratory results, pharmacy data, and comorbidity data, Disease registries have become an essential technological component of Meaningful Use (MU) of electronic health record (EHR) systems. Despite the availability of evidence-based guidelines for the care of the children with diabetes mellitus, there remain large and widespread gaps between expert recommendation and the actual delivery of care.
The aim of the study to evaluate of the current international registry update specifically for the children and adolescents following regularly in diabetes clinic Pediatric hospital (PADU), Ain Shams University during a period of six month and updating the existing electronic medical record (Database) in diabetes clinic Pediatric hospital, Ain Shams University to provide measures improving patients outcome regarding both acute and chronic complication.
This study included 385 patients with 50.1% of them were females and 49.9% of studied group were males. Their mean age was 11.79 ± 4.16 years, and age of presentation in the studied group was ranging between 1-17 years.
The median daily insulin dose was 40 units per day ranging (23 – 56) units, the mean number of SMBG per day 3.360, number of studied patients which use analog as basal insulin was 276 patients and which use NPH was109 patient. The mean follow up HbA1c A after six months is 7.89 ± 1.48%, number of patient which developed hypoglycemia was 90 patients and number of patient which developed DKA was 120 patients.
The diabetic patients have associated chronic co-morbidity 98 of total screened patients, and duration of diabetes range (1-15), number of patients their duration of diabetes more than 5 years are 82 patients and number of patients their duration of diabetes less than or 5 years are 303 patients.
Comparing patients with longer diabetes duration (more than 5 years) and those with shorter diabetes duration (less than 5 years) there was significant difference between two groups regarding their HbA1c, HDL cholesterol, LDL cholesterol, hypoglycemia and DKA
Comparing patients with poor glycemic control and those with good glycemic control we found significant difference between them regarding frequency of hypoglycemia, which is more in patients with good control than those with bad glycemic control, and frequency of DKA which is more in bad control than good control and SMBG per day.
Regarding patients who inserted insulin pump there was significant improvement in their lipid profile, hypoglycemia and SMBG per day.
These registry data indicate that the majority of the patients with disease duration less than 5 years on regular insulin therapy, poor glycemic control was common and diabetic microvascular complications were observed in some cases.
This study showed the value of a registry system to enable monitoring of patients over many years. The study could be a first step in the development of a national registry system for diabetes in Egypt.