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Abstract SUMMARY A rthroplasty can fail because of aseptic loosening, instability, periprosthetic fracture or infection of the prosthesis. The incidence of periprosthetic joint infection is lower than aseptic loosening, but it is more serious and complex complication. Periprosthetic joint infection (PJI) after total joint arthroplasty procedures is a rare but devastating complication. Its management is challenging and costly, and requires special expertise for an optimal outcome. Hip and knee arthroplasty register gather information on patients that undergo a total joint arthroplasty and factors pertaining to their surgery which may affect their outcome for future years such as the reason for revision. Analysis of these data can help with the allocation of healthcare funds and the efficacy of on both the clinical and device side. The aims of the present study were to measure the infection rate, risk factors, in total hip arthroplasty (THA) and total knee arthroplasty (TKA) in an Egyptian community. This retrospective study included thirteen patients, eleven of them had undergone total knee arthroplasty and two cases had undergone total hip arthroplasty. Cases were obtained from the Egyptian community arthroplasty registry. Regarding the percentage of infection in knee cases and hip cases, the present study indicated that out of the 804 knee cases, 11 cases were reported to have infection representing 1.4% of the total knee cases. Out of the 700 hip cases, 2 cases were reported to have infection representing 0.3% of the total hip cases. Regarding the demographic characteristics of the studied cases, the present study indicated that the mean age of TKA patients were 67.50 years old while the mean age of THA patients were 47.50 years old. The male to female ratio was 1:1. Regarding the comorbidities of the studied cases, the present study indicated that 36.4% of the TKA cases had hypertension, 9.1% had hypertension and diabetics and 9.1% had rheumatoid arthritis. Regarding the type of organisms in TKA cases suffered from infection, the present study indicated that 9.1% of cases were infected with Staph (MRSA), 9.1% of cases were infected with coagulase negative Staph, 9.1% infected with Klebsiella and pseudomonas and 9.1% infected with Pseudomonas. Regarding the type of organisms in THA cases suffered from infection, the present study indicated that 100% of cases were infected with MRSA. The present study indicated that 12.5 % TKA patients received either Ceftriaxone or Ciprofloxacin and Vancomycin, 18.2% received either Ciprofloxacin or Maxipeme, and 36.4% received Vancomycin. Our results indicated that 50% of THA patients were treated with Amikacin and 50% were treated with Ciprofloxacin. Regarding the procedure among studied groups, our results showed that 72.7% were Debridement & Retain, 9.1% was Poly exchange (late infection) and 18.2% were complete revision among knee cases but among hip cases all of patients were complete revision. Regarding the laboratory findings among the studied cases, our results showed that the mean ESR was 90, mean CRP was 95, mean of WBCs was 7.55 among knee cases group, and the mean of ESR was 62.5, mean of CRP was 46.70, mean of WBCs was 5.90 among Hip cases group. |