الفهرس 
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Abstract
ENGLISH ABSTRACT
Background: Scars widen when the overlying musculature (frontalis muscles, procerus, and
corrugator supercilii muscles) pulls apart suture lines. Because Botulinum Toxin A (BTA) is
known to prevent fibroblast proliferation and it also induces temporary muscle paralysis, the
purpose of this current study was to evaluate the beneficial effects of Botulinum toxin type A
(BTA) on scar formation.
Study objective: To evaluate the efficacy and safety of early postoperative Botulinum Toxin
type A injection on improving vertical or oblique facial scars.
Materials and methods: Twelve patients were selected randomly presenting with a recent
vertical or oblique forehead lacerations. The sample was selected to match a list of inclusion
and exclusion criteria and randomized into two groups: One group (n =6) received BTA
injection within 5 days of primary closure and the other group (n = 6) received no further
treatment. Assessment included measurement of wound width, Vancouver scar scale and
L*a*b* Color difference between the scar and surrounding normal tissue (ΔT), along with
clinical photographs.
Results: There was significant improvement in the VSS and less increase in the wound width
in the patients treated with BTA injections compared to the control group. All the significant
changes were observed at the 3 and 6-month visits, but not at the 1-month visit. All cases
showed uneventful healing.
Conclusion: This study showed that when BTA injections are administrated during the early
postoperative days it shows great improvement in the scar quality.