Search In this Thesis
   Search In this Thesis  
العنوان
Synthesis, Biological Evaluation and Electrochemical Studies
of Some Acridine Derivatives/
المؤلف
Asmaa Basiouny Mohammed Sallam
هيئة الاعداد
باحث / أسماء بسيوني محمد سلام
مشرف / مجدي عبد العظيم كامل
مشرف / إبراهيم الطنطاوي السيد
مشرف / خالد محمود حسن
الموضوع
Chemistry Classification of dyes Conducting polymers Organic measurements Textile Printing
تاريخ النشر
2022.
عدد الصفحات
129 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
Organic Chemistry
تاريخ الإجازة
8/3/2022
مكان الإجازة
جامعة المنوفية - كلية العلوم - الكيمياء
الفهرس
Only 14 pages are availabe for public view

from 148

from 148

Abstract

Heterocyclic compounds containing nitrogen atom are one of the most
important resources for new drugs. They are used to develop a new azodyes based
on acridine chromophore for applications in printing and in-vitro antibacterial
screening. Furthermore, the electrochemical measurements were studied and
achieved to identify the electrochemical behavior of the azo-disperse dyes. The
electrochemical degradation was also studied.
This thesis contains three parts.
Part One
The introduction part represents a general background on acridine
compounds, biological applications and its analogues. It is also illustrate a brief
background concerning dyes, their classifications, electrochemical detection,
harmful effects on environment and an electrochemical method for their removal.
Part Two
It describes the experimental section which contains the methodology,
materials and solvents for the preparation of acridine disperse-dyes for organic and
electrochemical studies. Furthermore, acridine azocompounds characterization
were studied by FT-IR, NMR, and mass spectral analysis.
The application of these dyes on polyester fabrics was also studied. The invitro anti-bacterial screening of the printed dyes towards Gram (+) and Gram (-)
pathogens was also recorded. In addition to, the preparation of poly1,2-DAAQ/GC
electrode and the electrochemical behavior and degradation of azodye 10c, CPE
analysis and UV-Vis analysis were illustrated.
Part Three
Illustrates results and discussion part of the synthetic methods of acridine
dyes and the spectroscopic analysis for the azo compounds. Development methods
for the synthesis of the disperse dyes and suggested mechanisms for the formation
of the final products were also mentioned and discussed. In addition to, the
electrochemical behaviour of 10c using GC electrode and poly 1,2-DAAQ/GC
electrode was performed. The effect of scan rate, concentration and analytical
measurements were detected.
The removal of dye 10c was conducted using controlled potential
electrolysis (CPE) technique at the both mentioned electrodes. These experiments
were followed by using UV/Vis technique before and after removal treatment.