الفهرس | Only 14 pages are availabe for public view |
Abstract Uterine myomata are the most frequent tumours of the female genital tract affecting 20-50% of all women, with an increased incidence in the later years of a woman‘s reproductive life. Myoma is mostly asymptomatic. Size and location are the main factors that determine if a myoma leads to symptoms and problems. Important symptoms include abnormal uterine bleeding, abdominal discomfort, bloating, painful defecation, backache, urinary frequency or retention and infertility. Patients have multiple options in the management of uterine myomas including observation, medical therapy, uterine artery embolization, high intensity focused ultrasound ablation and as well as surgical methods like myomectomy and hysterectomy. Surgical removal is necessary when the myoma is symptomatic and resistant to medical management or interferes with reproduction. Although uterine artery embolization is now an effective way for managing symptomatic uterine myomas but its effect on future conception remains unclear. There are various pharmacological and nonpharmacological methods have been tested to control haemorrhage during myomectomy. However, no specific procedure or drug has been identified as the optimum management method to decrease bleeding during these operations. This study was conducted at Tanta University Hospitals aiming to compare between the effect of intramyometrial injection of carbetocin versus vasopressin for reduction of blood loss in cases of myomectomy operations. We included a total of 60 patients diagnosed with uterine fibroids, and they were divided into three equal groups; Control group (20 cases), Carbetocin group (20 cases) and Vasopressin group (20 cases). |