الفهرس 
EtiologyOnly 14 pages are availabe for public view
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Abstract
Summary Sepsis results in vasodilatation associated with cardiac dysfunction. Fluid therapy poses an important step in managing this acute circulatory failure and reversing morbidities. However, this created the need to predict fluid responders to optimize fluid resuscitation and organ support therapies. Increase in CO emerged as an acceptable surrogate for positive fluid response. The ideal CO monitor should be safe, low-cost, painless, non-invasive, easy to use and interpret and allow for the continuous, hands-free acquisition of accurate data. Many studies have validated TTE as a reliable technique for CO monitoring. Some disadvantages of TTE include the need for expensive, bulky equipment and adequate training to obtain accurate VTI with non-continuous acquisition of data. EC is a type of thoracic bioimpedance. EC has some of the criteria of ideal CO monitor: safe, non-invasive, continuous reading, non-operator dependent, don’t prerequisite long learning curve to use. Previous studies revealed that agreement between EC and PAC is clinically acceptable, and they can be used interchangeably in patients scheduled to undergo coronary artery surgery necessitating the placement of PAC and in pediatric patients with congenital structural heart disease. We conducted this study to validate EC use in a special category of critically ill patients in whom dynamic fluid responsiveness is of clinical value in the management. The aim of this study is to evaluate the diagnostic accuracy of EC for the noninvasive determination of fluid responsiveness in sepsis and agreement of EC compared to TTE. The primary outcome was the diagnostic accuracy of