الفهرس 
INTRODUCTIONOnly 14 pages are availabe for public view
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Abstract
The neuro-ophthalmic findings in patients with IIH are mainly visual impairment and papilledema. Papilledema is caused by increased ICP and is a cardinal sign of IIH. Although OCT is frequently used in clinical practice to evaluate thinning of the RNFL due to optic nerve injury from a variety of causes, using OCT to quantify papilledema is relatively new. Evaluating OCT findings in IIH patients and comparing it with clinical and perimetric findings could be useful.
A prospective, cross sectional, non-interventional, non-randomized study was carried out on 20 eyes in referred patients suspected for or diagnosed with IIH. In all patients a detailed ophthalmic and systemic evaluation was performed. The grade of papilledema was assessed using MFS on colored fundus photography pictures and then perimetry and OCT studies were done.
There were 3 cases with grade 0 (15%) which means that no clinical papilledema was identified. Average RNFL thickness was significantly greater in the moderate/severe PO group than the control group. Likewise, average RNFL thickness was significantly greater in the moderate/severe PO group than the mild PO group. However, there was no significant difference between RNFL thickness in the mild PO group compared with the control group. PTR thickness value was significantly greater in the moderate/severe PO group than the control group, and in the Moderate/severe PO group than the mild PO group. Moreover, PTR thickness was significantly greater in the mild PO group versus the control group. No significant difference was found between GCL thickness in mild PO cases compared with controls, but GCL was significantly thinner in the moderate PO and severe PO cases versus control group. Comparing GCL thickness in mild PO cases with moderate PO cases a significant difference was found similarly GCL thickness was significantly thinner in severe PO cases compared with mild PO cases, but so significant thinning was found in GCL between moderate and severe PO cases. No correlation was found between MD of the perimetry and grade of papilledema from colored fundus photographs in eyes with mild grades of papilledema. Lastly, there was no correlation between MD of the perimetry and GCL thickness of the OCT in eyes with mild papilledema but there was a positive correlation between MD of the perimetry and GCL of the oct in eyes with moderate/severe papilledema.