الفهرس 
IntroductionOnly 14 pages are availabe for public view
 |  | from | 132 |  |  |
| | | from | 132 | | |
Abstract
Behçet’s disease (BD) is a multisystemic chronic vasculitis characterized by recurrent skin lesions, oral and genital aphthous ulcerations, arthritis, and uveitis. optical coherence tomography (OCT), a noninvasive, noncontact, transpupillary imaging modality that can show structural changes even in micrometer level, provides detailed information about these changes in BD with posterior segment involvement. This study was conducted to compare posterior segment OCT findings in Behçet’s disease patients without clinically detected ocular involvement to that of age and sex matched normal subjects. This study included 24 cases with non-ocular BD and 18 healthy subjects as a control group who were recruited in outpatient clinic of Mansoura university Ophthalmic Center over one year from September 2019 and August 2020. After obtaining a written informed consent, the cases were subjected to full history taking and full ophthalmological examination including assessment of visual acuity, slit lamp examination and examination by autorefractometer. Spectralis spectral domain optical coherence tomography (OCT) was used to obtain retinal images. The results of this study showed that: There was no statistically significant difference in the mean age and sex distribution between the cases in the two study groups. There was no statistically significant difference in the total retinal volume between the cases in the two study groups. There was no statistically significant difference in the total retinal thickness in the different retinal regions between the cases in the two study groups. There was no statistically significant difference in the retinal nerve fiber layer in the different retinal regions between the cases in the two study groups except the inner inferior region and outer superior region that were statistically significantly lower in the BD group. There was no statistically significant difference in the Ganglion Cell Layer in the different retinal regions between the cases in the two study groups. There was no statistically significant difference in the Inner Plexiform Layer in the different retinal regions between the cases in the two study groups. There was no statistically significant difference in the minimum rim width in the different optic disc regions between the cases in the two study groups except the temporal region that was statistically significantly higher in the BD group. There was no statistically significant difference in the mean pRNFL in different optic disc regions between the two study groups. The mean center line thickness in the BD group was statistically significantly higher as compared with the control group.