الفهرس 
IntroductionOnly 14 pages are availabe for public view
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Abstract
Traumatic brain injury is a major cause of death and disability
worldwide, causing significant financial burden. Although CT and MRI
are used to determine the extent of brain injury, they cannot predict the
impending risk of cerebral vasospasm or hypo perfusion, which is
essential to evaluate the risk of secondary neurological deterioration and
to start goal directed therapy if needed. Transcranial Doppler sonography
can serve the purpose of monitoring cerebral hemodynamics immediately
after traumatic brain injury. It is the only non-invasive imaging modality
that can detect reduced blood flow velocities, elevated pulsatility index,
and vasospasm, which are indicators of poor patient outcome. It is costeff
ective, non-invasive, portable, and allows continuous or repeated
monitoring in ICU.
Therefore, we carried out this research work on patients with early
traumatic brain injury to establish the relation between Doppler findings
and the prognosis. The objectives of this study were to:
assess the predictive value of early transcranial Doppler
sonography in patients with traumatic brain injury in terms of
secondary neurological insult.
establish a comparison between transcranial Doppler sonography
and other non-invasive modalities as predictors of outcome in those
patients.
The study protocol was approved from the Ethics Committee of the
Faculty of Medicine, Menoufia University, and informed written consents
were obtained from the patients or their guardians.
The study enrolled adult (≥ 18 years-old) patients with mild and
moderate traumatic brain injury. We excluded patients who had previous