الفهرس | Only 14 pages are availabe for public view |
Abstract ACS describes the spectrum of clinical manifestations which follow disruption of a coronary arterial plaque, complicated by thrombosis, embolization and varying degrees of obstruction to myocardial perfusion. It is usually one of three diseases involving the coronary arteries: ST-segment elevation myocardial infarction (STEMI), non-ST-segment elevation myocardial infarction (NSTEMI) and unstable angina (UA) (DeVos and Jacobson, 2016) . Chest pain affects 20% to 40% of the general population during their lifetime. Each year, approximately 1.5% of the population consults a primary care physician for symptoms of chest pain. The rate is even higher in the emergency department, where more than 5% of visits and up to 40% of admissions are because of chest pain. (Hoorweg et al., 2017) Chest pain is often the presenting symptom of myocardial infarction (MI), which is damage to the cardiac muscle caused by ischemia. 3 This can be caused by a thrombotic occlusion of a coronary vessel (type 1) or by the myocardial oxygen demand surpassing the oxygen supply (type 2). (Thygesen et al., 2012) |