الفهرس | Only 14 pages are availabe for public view |
Abstract This thesis includes three chapters: the first of which deals with the role of multicomponent reactions (MCR) in assisting organic synthesis which deals with coupling between more than two reactants in a one-step to form a new product. Compared to the classical multistep organic reactions, MCR provide high atom efficiency and accessibility to a large number of molecules with wide structural diversity. The simple and straightforward experimental procedure of MCR is a major advantage; putting them in a lead position in the future.It deals with the conversion of isocyanides into their corresponding compounds. Multicomponent reactions have great applications for organic chemistry synthesis. Isocyanides (isonitriles) are stable organic species with a formally reactive divalent carbon can react as nucleophile or electrophile. Isocyanide group differ from the other organic functional groups, due to its considerable reactivity and broad field of organic applications, that’s why make us think about using it to synthesize the novel α-aminoacyl amide. |