الفهرس 
IntroductionOnly 14 pages are availabe for public view
 |  | from | 134 |  |  |
| | | from | 134 | | |
Abstract
This study aimed to compare the biocompatibility and sealing ability of an experimental tricalcium phosphate cement versus Biodentine and MineralTrioxide Aggregate used for furcation perforation repair in dogs.
For comparison of the biocompatibility, Perforations were done in 60 teeth (premolars and molars) of six adult dogs. Animals were divided randomly into 3 equal groups of 2 animals each according to the post-operative evaluation period into 1 week, 1 month, and 3-months. Every group was further subdivided into 4 subgroups according to either being repaired with: the experimental tricalcium phosphate cement (n=6), Biodentine (n=6), Mineral Trioxide Aggregate (MTA) (n=6), and positive control(n=2). After evaluation periods, tissue blocks were harvested and histologically examined. No statistically significant difference was found regarding bone deposition scores and inflammatory reaction in the three groups after 1 week, 1 month or 3 months. All three groups showed statistically significant difference between all three time periods. Regardless of the repair material used, inflammation scores at 1-week showed the highest scores, it decreased over time except for the control group.
For comparison of the sealing ability, ninety-six extracted human molars were perforated in furcation area and unsystematically divided into four groups
relative to the furcation repair material into: experimental tricalcium phosphate (n=30), Biodentine (n=30), MTA (n=30) while the fourth group of samples was left unrepaired as control (n=6). Each group was further subdivided into three subgroups according the evaluation period as 1 week, 1 month and 3 months. Samples were subjected to dye penetration test and values calculated using a stereomicroscope with magnification (25X). Kruskal Wallis test was utilized to show the difference between more than two groups in non-related samples. Biodentine group showed statistically significant least dye absorbance; statistically there wasn’t a significant difference between the Experimental material and MTA.
Within the limitations of the current study, it could be concluded that;
1- The experimental Tricalcium phosphate cement, showed promising results with evidence of healing by new bone deposition and few inflammatory cells at the perforation site when used as perforation repair material and can be considered as a successful treatment options for repairing furcation perforations with lower cost and shorter setting time than MTA.
2- The experimental tricalcium phosphate provides an easy handling and quick setting repair material with comparable biocompatibility and sealing ability to MTA and could be considered as a successful treatment option for repairing of furcation perforation.