![]() | Only 14 pages are availabe for public view |
Abstract RDS is a clinical diagnosis which warranted in a preterm newborn with respiratory difficulty. The primary cause of RDS is inadequate pulmonary surfactant as the immature structure and surfactant-deficient lung has decreased compliance and a tendency to atelectasis. Researches on animal study the role of vitamin D on regulating the maturation of the rate lung epithelium and suggestted that 1 alpha,25(OH)2D3 is a local mediator of epithelial-mesenchymal cell interactions in the developing rat lung and that 1 alpha,25(OH)2D3 might be therapeutically useful in treating the respiratory distress syndrome of premature neonates. although there are huge number of studies that link vitamin d to infection, different chronic illness, little attention was paid to the link vitamin d to the neonatal lung, recently a study on neonates with TTN found that the serum levels of 25(OH) D3 were significantly lower in infants with TTN compared to infants with no respiratory distress. |