الفهرس 
INTRODUCTIONOnly 14 pages are availabe for public view
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Abstract
Prolonged catheterization is considered the main cause of catheter associated urinary tract infection.
The aim of this prospective study was to investigate the role of noble metal alloy coated catheter in diminution of bacterial colonization and prevalence of urinary tract infection in patients with prolonged catheterization (more than 2 weeks).
The current study was carried out on 100 patients at Alexandria main hospital urology out patients clinic from 21 may 2020 to 21 December 2020. Patients divided into 2 equal groups, group A with noble metal alloy catheter and group B with silicone foley catheter.
After full informed consent, all patients underwent Complete aseptic catheterization technique, Urine sample collection for culture and analysis, complete blood picture (CBC), erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP) at day zero, ten and twenty post catheterization.
The results were tabulated and analysed comparing 2 groups at three time points.
The mean CRP decreased from 38.98 on the 1st visit to 11.06 on the 3rd visit in the 1st arm and increased from 15.45 on the 1st visit to 20.67 on the 3rd visit in the 2nd arm.There is a significant reduction along time only in the first arm, where the p value is.008.
The mean pain score decreased from 2.84 on the 1st visit to 1.08 on the 2nd visit and to 1.10 on the 3rd visit in the 1st arm and decreased from 3.00 on the 1st visit to 2.20 on the 2nd visit and to 2.48 on the 3rd visit in the 2nd arm.
As regard to the incidence of haematuria on the second visit being 0% and 6%, respectively, with a significant difference of p =.027, and the total cases of haematuria along the being 0% and 14%, respectively, with a significant difference of p =.0125.
By the end of study, all of patients was bacteruric thise revealed that noble metal alloy catheter has no effect on asymptomatic bacteruria.
The most frequent isolated organism from both group was Enterobacteriaceae member species (E.COLI).
The incidence of CAUTI was 4% in the first arm and 18% in the second arm. there is a statistically significant difference between the two arms, where p =.025 with a corresponding relative risk reduction of CAUTI by 77% among patients on first arm treatment.
Analysis of different variables in cases of CAUTI showed that 25% of females have CAUTI while 9.1% of males have CAUTI.Among diabetics rate of CAUTI 26% versus 8.2% in non diabetics with statistically significant difference (p=0.035*).
Finally we concluded that silver metal alloy catheter is very effective in prevention of CAUTI in long term catheterization but has no effect on incidence of asymptomatic bacteruria.