الفهرس 
AcknowledgementOnly 14 pages are availabe for public view
 |  | from | 83 |  |  |
| | | from | 83 | | |
Abstract
autologous PRP has become an attractive nonsurgical option for a broad
spectrum of medical disorders including gynecology and obstetrics in
view of it being a noninvasive, affordable, simple, easy to perform and
being effective with the idea that platelets are the normal products of
blood involved in achieving haemostasis at the time of bleeding with their
ability to release multiple growth factors and other substances.
This review has reviewed how we can utilize it for wound healing
like in LSCS, refractory cases of lichen sclerosus, recurrent
implantation failures (RIF) with or without thin endometrium. It seems
to be giving a new ray of hope for those who have very poor ovarian
reserve or in cases of POF although in budding stage, it might become an
alternative for those who do not want to undergo donor IVF. Further this
might also obviate the need for an IVF with natural conceptions reported
following this in those where previous >= 3 ivf had failed in view of
poor ovarian reserve. Patients having endometrium destroyed secondary
to tuberculosis or other causes of severe resistant Asherman’s syndrome
where along with menstrual stem cells combined with PRP might
help in regaining natural endometrial growth and subsequent
pregnancy.
The risks of PRP with regard to infection bleeding and nerve damage
seemed to be minimal. Only till now most studies have been case
studies, pilot studies and thus large randomized trials are needed for it
to become a permanent therapy for these refractory cases .
Conclusions
Platelet-rich plasma is an exciting new technology that may have the
potential to serve as an alternative or adjuvant treatment to surgery in
many common injuries/conditions in gynecology and obstetrics.
In the field of gynecology and obstetrics, the few studies that have
been conducted are pilot studies, case series, and case reports. The risks
of PRP therapy as infection, bleeding, and nerve damage, appear to be
minimal.
The use of PRP in the clinical settings should be reserved to research
projects only .
Care should be taken when reading the literature as not all that
glitters is gold .
sdocaadeemmoceR
Recommendations Large randomized controlled studies are required to confirm its efficacy and safety in various gynecological disorders.