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العنوان
The epidemiological profile of juvenile idiopathic artheritis :
المؤلف
Sobh, Neven Nashat.
هيئة الاعداد
باحث / نيفين نشأت صبح
مشرف / أحمد محمود الرفاعي
مشرف / دينا شاهين
مشرف / أحمد درويش محمد ابراهيم
مناقش / رشا عبدالملك العشري
مناقش / دعاء يوسف محمد
الموضوع
Juvenile Idiopathic Arthritis. Rheumatoid arthritis in children. Arthritis, Juvenile Rheumatoid. Arthritis, Juvenile Rheumatoid - Therapy.
تاريخ النشر
2021.
عدد الصفحات
online resource (134 pages) :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
طب الأطفال ، الفترة المحيطة بالولادة وصحة الطفل
تاريخ الإجازة
1/1/2021
مكان الإجازة
جامعة المنصورة - كلية الطب - قسم طب الأطفال.
الفهرس
Only 14 pages are availabe for public view

from 134

from 134

Abstract

Juvenile idiopathic arthritis (JIA) is the most common type of arthritis in children. It is a chronic disease. This means it will probably last a long time. This arthritis causes swelling pain with movement and possible decreased motion in the joint. There are seven types of JIA. The three major types include: Oligoarticular JIA (arthritis in four joints or less), Polyarticular JIA (arthritis in five or more joints) and Systemic JIA (arthritis plus fever, rash and large lymph nodes). The aim of the present study was to determine the prevalence, subtypes, distribution, and characteristic features of JIA among children of Mansura university children’s hospital Rheumatology outpatient clinic. The present study was Cross-sectional observational study carried out in MUCH rheumatology outpatient clinic, from April 2019 to April 2020. Patient diagnosed with JIA according to International League of Associations for Rheumatology (ILAR). All patients in our study were subjected to : History, clinical examination, therapeutic history, eye examination and serological study. The study showed that : There was statistically highly significant difference between JIA types as regard Age, age of onset of disease, duration of the disease affected at time of diagnosis with highest value in psoriatic type. There was statistically highly significant difference between JIA types as regard fever, rash and organomegally with increase in systemic onset rather than other types . While ophthalmic affection show no significant difference between JIA subtypes. There was statistically significant difference between WBCS, PLT, SGOT, SGPT, CRP, ESR among JIA subtypes with the highest value in systemic onset while HB was lowest value in systemic onset while HLAB27, ANA, RF , CR show no significant difference. There was statistically significant difference in MTX, Humera, Enbrel and leflunomaide usage between JIA subtypes. PLT, CRP, ESR1 correlated significantly with severity of the disease while other laboratory parameters had no significant effect. MTX, Pulse steroid, Actemra and Lefluonamide usage differed significantely according to the severity of the disease while Humera, Endoxan, Enbrel, NSIAD Show no significant difference. The characteristics of JIA in Egyptian show higher frequency of the disease in rural areas. Effective system was available in our study shown in minimal effect of the disease on patient disability, deformity, mentality, weight and height. Conclusion: There was statistically highly significant difference between JIA types as regard fever, rash and organomegally with increase in systemic onset rather than other types . While ophthalmic affection show no significant difference between JIA subtypes. Regular investigations and follow up were available in our hospital which helps in decreasing drug complications and easily assessment of patients with drug resistance or remission.