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العنوان
Role of Preoperative DWI-MRI and Dynamic Contrast Enhanced MRI in Predicting Aggressive Disease in Endometrial Carcinoma/
الناشر
Ain Shams University.
المؤلف
Ali,Hebatullah Ezzat Mahfouz .
هيئة الاعداد
باحث / هبة الله عزت محفوظ علي
مشرف / شيرين قدري أمين
مشرف / بسنت محمد رئيف مسعد
تاريخ النشر
2021
عدد الصفحات
186.p;
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
الأشعة والطب النووي والتصوير
تاريخ الإجازة
1/10/2021
مكان الإجازة
جامعة عين شمس - كلية الطب - Diagnostic Radiology
الفهرس
Only 14 pages are availabe for public view

from 186

from 186

Abstract

Background: Endometrial cancer is the most common gynecologic cancer seen in women today, It is more prevalent in high-resource countries, but its incidence is rising in low-resource countries as a result of rising obesity and improved longevity.
Aim of the study: The purpose of this study is to evaluate the accuracy of DWI and dynamic contrast enhanced MRI in preoperative staging of endometrial carcinoma and prediction of severity of the disease prior to surgery.
Patients and Methods: The study included 20 patients referred from the Gynecology Department to the Radiology Department in Ain Shams University hospitals from October 2020 to July 2021. They were all presented with postmenopausal bleeding or menorrhagia.
Results: The current study showed that as regard MRI signal characteristics in the studied group; 45% were isointense in relation to myometrium on T2WI. 100% revealed high signal intensity (restricted diffusion) on DWI. 100% had ADC value < 1.2 × 10-3mm2/s. There was no significant association between histological grade of endometrial carcinoma and the ADC value of each grade. There was highly significant difference between MRI Staging and Surgical Staging. There was no significant difference between MRI findings and Surgical Findings.
Conclusion: DCE-MRI and DWI represent valuable supplements to conventional MRI by providing preoperative imaging biomarkers that predict aggressive disease in endometrial cancer patients.