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Abstract Acute kidney injury is a common clinical situation with serious complications with long term and short term negative consequences as regards morbidity and mortality. This study was carried out in Sohag University Hospital to check AKI incidence and patient characteristics, hence planning for better patients’ outcome. Many clinical and laboratory parameters for all patients were evaluated, including: full history and detailed clinical examination, laboratory investigations and ultrasound imaging of the kidneys then daily follow-up during hospital stay. Patients were classified according to treatment regimen into patients received supportive care and others received RRT then follow-up for 3 months after discharge. This study found that there was statistically significant relationship between patient age , history of diabetes, established CKD and AKI outcome. Also there was statistically significant relation between AKI outcome and increased S.Creatinine level, elevated white blood cells count, decreased Hemoglobin level and increased serum potassium level. As regards the staging of AKI, We found statistically significant relationship between AKI outcome and staging of studied population as stage 3 had worse outcome . Also we found statistically significant relationship between AKI outcome and ultrasound grading of echogenecity of studied population as increased echogenicity had worse outcome than normal kidneys . Conclusions Our study concluded that mortality and morbidity in patients with AKI increased in advanced age, diabetic, CKD patients and in patients with anemia, leucocytosis hyperkalemia and increased serum creatinine. Limitation of study • Limitations associated with S.Creatinine for assessement of renal recovery, such as loss of muscle mass, changes in volume of distribution, changes in renal reserve and hyper filtration . • The limited number of studied cases. • The limited time of the study. Recommendations • Conduction of further studies of AKI in wide scale of patients and in a long periods. • Regular education of the public and health care workers should be done in order to get early diagnosis and treatment of AKI. |