الفهرس 
Introduction and RationaleOnly 14 pages are availabe for public view
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Abstract
Surgical site infections (SSI) are the most common and costly
of all hospital-acquired infections. Resections of colonic and rectal
segments have been associated with the highest rates of SSI amongst.
Negative pressure wound therapy (NPWT) is a relatively new
treatment option which considered in our study to decrease surgical
nosocomial events in elective paediatric colorectal procedures in
comparison with the standard wound care. A randomized control
study was conducted in paediatric surgery department. Lower
statistical difference of infection frequency in NPWT group
comparing to standard wound care group was revealed.
A prospective randomized control single blind (patient) trial
was conducted in paediatric surgery department at Ain Shams
University, Cairo, and Suez Canal University, Ismailia, Egypt
hospitals in a period of two years. Simple randomization (tables)
method was used to enroll patient younger than twelve years old who
had post colorectal procedures (closure of stoma, primary resection &
anastomosis of bowels). Immunocompromised, chronic ill debilitated
and patient with bowel perforation on table were excluded from the
study. Sociodemographic data, clinical examination and preoperative
investigation were obtained for all included patients. Postoperative
follow up was maintained to assess the incidence of SSI within 30
days of surgery according to CDC criteria of SSI. Secondary
outcomes assessed will include the follow up of the surgical site
infection to assess and evaluate its condition, drain and culture of its
discharges. Additional secondary outcomes assessed will include the
length of hospital stay. We enrolled 300 children who underwent a
colorectal procedure. The study population was randomly allocated
into two groups: group A: standard wound care (n=150), group B:
negative pressure wound care (n=150). There was no statistical
difference among the different group according to baseline
characteristics and lab investigation. There was no statistical
difference among the different group according to the surgical
procedures. There was significant difference between the two groups
according the frequency of infection (P value >0.001). Also, subgroup
analysis regarding to the age group showed significant difference
according to the frequency of the complication. Regarding
hospitalization, there was statistical difference of the duration of
hospitalization (P value 0.001). there was no statistical difference
among the different group according to the frequency of infection, and
results of culture of the discharged infection.
Our study concluded that NPWT use in the colorectal surgical
procedure in pediatric has beneficial in the setting of decrease the
incidence of SSI and the need for hospital stay post-surgery