الفهرس 
LITERATURE REVIEWOnly 14 pages are availabe for public view
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Abstract
Abscisic acid (ABA) is a phytohormone that regulates numerous developmental processes and adaptive stress responses in plants. It can be produced and released from many animal and human cells (immune, cardiovascular, stem and pancreatic cells) under physiological or pathological conditions. Recent studies suggest a role of ABA regulating immune response and insulin action. Under the light of these studies we hypothesized that ABA could have protective effect in a model of neuroinflammation.This study was divided to a chronic and acute experiment. We chose a model that involved feeding the animals with a High Fat Diet (HFD); this model induces glucose resistance and an increase of proinflammatory markers in peripheral tissues, and nervous system, where we administered ABA in the drinking water.