الفهرس 
INTRODUCTIONOnly 14 pages are availabe for public view
 |  | from | 53 |  |  |
| | | from | 53 | | |
Abstract
Differentiated thyroid carcinoma (DTC) is rare but remains the most important endocrine children malignancy. The incidence is increasing globally, mainly due to increased detection, but this does not fully explain the increase in cases and a real increase cannot be ruled out. However, DTCs in children / adolescents are not linked with a higher mortality rate (less than two percent disease-specific mortality long-term) due to the response to management. Our study aimed to evaluate the prevalence of differentiated thyroid cancer in children and adolescents.
In the present study we report the characteristics and outcome of a series of 50 differentiated thyroid cancers. Regarding Type of surgery, Total thyroidectomy was done for all cases. Ultrasound was done for All cases without Chest X-ray. Regarding Clinical characteristics, 52.0 % was LT and 48.0 % was RT side. 62.0 % showed Positive Lymph node involvement and 38.0 % Negative. CN/LV % was CN/LV and 10.0 % was LV. In the present study, mean TSH was 3.27 ± 2.06, mean T4 was 1.24± 0.41, mean T3 was 3.56± 1.10, and mean Thyroid antibodies was 49.48± 29.07.
In the present study, regarding Histological type, 96.0 % of cases showed Papillary and only 4.0% was Follicular. In the present study, 12.0 % of cases showed Recurrence without metastasis in Bone, Visceral, or Both.
Regarding Gender, Age (years), Side, Histological type, TSH, T4, T3, Thyroid antibodies, and Postoperative thyroglobulin level there was a statistically a non-significant difference between Recurrence and Gender, Age (years), Side, Histological type, TSH, T4, T3, Thyroid antibodies, and Postoperative thyroglobulin level. Gender, Age (years), Side, and Histological type do not predict outcome.
In the present study, Regarding Lymph node involvement, there was a statistically a significant difference between Recurrence and Lymph node involvement. Positive Lymph node involvement of 12% showed recurrence.