الفهرس 
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Abstract
Background: Many children experience dental anxiety during dental treatment.
Conscious sedation is used to alleviate anxiety and enhance a child’s cooperation.
Aim: This study aimed to compare the efficacy of intranasal versus sublingual
dexmedetomidine.
Design: Forty-two
healthy, uncooperative children participated in the study. They
were divided randomly into two groups: In the first visit, group I received intranasal
dexmedetomidine and group II received sublingual dexmedetomidine, whereas
at the second visit, the alternate route was implemented in a crossover design. The
child’s acceptance of drug administration method was assessed using a 4-point
rating
scale. Time until optimum sedation was measured. Anxiety during local anesthesia
administration was scored using Venham’s rating scale. Postoperative response was
recorded through Vernon et al’s questionnaire.
Results: The Modified Vernon et al questionnaire that was answered by the parents
24 hours after the dental visit through the phone showed that there was no negative
effect on postoperative behavior of children.
Conclusions: Both routes prevented the increase in anxiety scores equally during
local anesthesia and do not have negative effect on postoperative behavior of children.
However, the sublingual route showed better acceptance with longer onset time
of action than the intranasal route.
KEYWORDS
dental anxiety, dexmedetomidine, sedation