الفهرس 
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Abstract
This thesis comprises four chapters. The first chapter is the introduction which involves a general literature review on oxadiazole and thiadiazole derivatives and studying their different reactions The second chapter is devoted in a detailed discussion of the results obtained throughout the work by the candidate; in which D-glucose reacted with ethyl 3- oxobutanoate (ethyl acetoacetate) in neutral medium, to afford ethyl 5-(1,2,3,4- tetrahydroxybutyl)-2-methylfuran-3-carboxylate 243.