الفهرس 
Helicobacter PyloriOnly 14 pages are availabe for public view
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Abstract
Background: H. pylori infection has become highly resistant to traditional first-line treatment regimens because of antibiotic resistance coupled with poor patient compliance with completing the treatment course. Many clinical studies proved that nitazoxanide (NTZ) was found to be well tolerated by humans, with an encouraging rate of eradication when it was administered with omeprazole, Aim and objectives; to evaluate the efficacy of nitazoxanide and doxycycline as a rescue therapy in treatment of H.pylori, Subjects and methods; This study is an prospective observational cohort study, was carried out on 70 patients at outpatient clinic: Hepatology and gastroenterology clinic of Internal Medicine Department– Ain Shams University hospital, from January 2021till June 2021, Result; There is significant difference between both studied groups as regards H.pylori Ag in stool 3 weeks after finishing course, Conclusion; LOAD therapy is preferable to clarithromycin-contained triple therapy in H. pylori infection eradication particularly in countries like Egypt with great clarithromycin resistance. This is at least until we can get the bismuth in our country. Recently, the increasing concepts about levofloxacin resistance and decreasing efficacy as a second line treatment directed us towards thinking in levofloxacin contained quadruple therapy including doxycycline and NTZ as alternative line of regimen therapy for better H. pylori eradication in our country