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العنوان
Biochemical study on the effect of some antioxidants on apoptosis in irradiated male rats =
المؤلف
Kodous, Ahmad Shehata Hashim Abdo.
هيئة الاعداد
باحث / Prof.Dr. Samir Mostafa Abd-El Aziz
مشرف / Prof.Dr. Nadia Zaki Shaban
مشرف / Late Prof. Dr. Ahmed Moustafa Zahran
مشرف / Dr. Fatma Hassan El-Rashidy
الموضوع
Biochemical. Male Rats.
تاريخ النشر
2011.
عدد الصفحات
154 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
الكيمياء الحيوية ، علم الوراثة والبيولوجيا الجزيئية
تاريخ الإجازة
22/5/2011
مكان الإجازة
جامعة الاسكندريه - كلية العلوم - Biochemistry
الفهرس
Only 14 pages are availabe for public view

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Abstract

Male albino rats were whole body subjected to 2Gy every other day up to a total dose of 8Gy. Animals sacrificed on the 8th day after irradiation showed significant decreases in testis/body weight ratio. Biochemical analysis in testicular tissues showed significant decreases in SOD and CAT activities, concomitant with significant increase in XO activity and TBARS contents. Radiation exposure induced also significant increases in testicular DNA fragmentation, significant increases in mitochondrial NO and Ca+2 contents associated with significant decrease in nuclear GSH content. Testicular LDL-C content showed a significant increase which was much higher than its increase in serum, the content of HDL-C increased significantly, contrarily to serum where a significant decrease was recorded. Histological examination through electron microscope revealed apoptosis in testicular tissue.