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Abstract Summary Cicatricial alopecia represents a variety of skin diseases that create at their later stages permanent destruction of pigmented terminal hairs. They can create physical pain and severe emotional and psychological stress for patients. Effective safe medical therapy is a challenge for many patients. Platelet-rich plasma offers patients a potentially new therapeutic treatment option for scarring alopecia. So, the aim of this study is to compare the effect of platelets rich plasma on hair transplantation in treatment of cicatricial alopecia. This is a randomized control study that was performed on 15 patients with cicatricial alopecia at The Plastic and Reconstructive Surgery Department, Tanta University Hospitals from January 2018 to January 2019, after approval of the study by the local ethical committee and obtaining written fully informed consent from the patients. Patients with cicatricial alopecia in hair bearing skin and patients with any type of hair (silky, curly or normal hair) were included in the study. Patient with general debilitating diseases as diabetes or autoimmune diseases, patients with active skin diseases in recipient or donor sites, patients with no available donor sites and patients older than 50 years were excluded from the study. The alopecic area of each Patient was divided into two halves: 1st half (A): hair transplantation without PRP injection. 2nd half (B): hair transplantation after intradermal injection of autologous platelet rich plasma (PRP) in recipient site intra-operative and two weeks postoperative.Each patient was submitted to informed consent before participation, general examination, local examination of the donor and recipient sites and |