الفهرس 
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Abstract
Warts are epidermal tumors caused by HPV which are epithliotropic non-enveloped small double stranded DNA viruses.
Among the available medical and destructive therapeutic options for cutaneous warts, none is uniformely effective or vericidal. Aims of treatments are to cure the patient’s physical and psychological discomfort and to prevent the spread. The treatment is challenging and there is no single therapy established as completely curative.
The aim of this work to determine the efficacy of intralesional immunotherapy with bleomycin and PPD in common, palmar and planter warts.
Forty patients complaining from common, palmar and planter warts were enrolled in this study. They were selected from the attendants of out- patient’s clinic of dermatology (Assuit university Hospital).
The patients were divided into two groups, group A (20 patients) treated with bleomycin injection and group B (20 patients) treated with PPD.
Among patients in group A, 50% of the patients showed complete response while 35% of patients showed partial response and 15% no response to treatment.
There was significant reduction in size of lesions (0.000), as the mean size ± SD before treatment was (0.5-2cm2) and after treatment reached to (0.0-1.5cm2) with a mean percentage of improvement of (66.42±38.67).
There was also statistically significant reduction in number of warts after treatment (0.001) as the mean number of warts was 2.05±3.12) before treatment and become (1.10±2.85) after treatment, with mean percentage of improvement 56.50±47.37%.
Regarding common warts in group A our results show that 5 patients (62%) had complete response, 3patients (37.5%) had partial response.
Regarding palmar warts in group A our results show that 1 patient (25%) had complete response, 2 patients had partial response and 1 patient (25%) had no response to treatment.
Regarding planter warts in group A our result shows that 4 patients (50%) had complete response, 2 patients (25%) had partial response and 2 patients (25%) had no response to treatment.
Among patients in group B, 50 % of patients showed complete response to PPD while 30% of patients showed partial response and 20% no response to treatment.
There was significant reduction of size of lesion (0.000) as the mean size ± SD before treatment was (0.91±0.47 cm²) and after treatment reach to (0.39±0.55 cm²) with a mean percentage of improvement of 62.33±41.62%.
There was also statistically significant reduction in number of warts after treatment (0.000) as the mean number of warts 1.25±2.53 before treatment and become 61.83±43.13%.
Regarding common warts in group B our results show that 4 patients (44.4 %) had complete response, 4 patients (44.4%) had partial response and 1 patient (11.1%) no response to treatment.
Regarding palmar warts 3 patients (75%) had complete response and 1 patient (25%) had no response to therapy.