الفهرس 
IntroductionOnly 14 pages are availabe for public view
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Abstract
Bacterial diseases are the main cause of high economic loss in aquaculture, particularly Gram-negative bacteria. A. hydrophila is considered the most prevalent gram-negative pathogen responsible for severe economic losses in freshwater fish. In addition, P. aeruginosa is the most common species associated with septicaemic infection in many fish species including freshwater fish. Overuse of antibiotics increases the risk of antibiotic resistance and multiply antibiotic resistance has become a public health problem. With the increasing occurrence of bacterial resistance against available antibiotics, it has now become necessary to investigate newer sources for antimicrobials. Endophytic fungi are considered a potential source of novel bioactive products.