الفهرس 
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Abstract
One of the challenges facing restoration of missing teeth is the unfavourable local condition of the alveolar ridge due to atrophy, which may cause insufficient bone volume in the horizontal and/or vertical dimensions. Many options for treatment of alveolar ridge defects are available, including varying surgical techniques as well as bone graft options. The technique and type of material used depend on the geometry and location of the defect.
Growth factors (GFs) are expressed during different phases of tissue healing and are therefore a key element in promoting tissue regeneration. Among many growth factors, Rich Plasma (PRP) and Platelet Rich Fibrin (PRF) have been developed.
The mineralized plasmatic matrix represents the next step in the evolution of platelets concentrate. The difference between MPM and other platelet concentrates (PRP and PRF) is the introduction of a mineral phase in the form of autologous bone or any other bony substitute.
In MPM, the resultant fibrin matrix is a fibrin network that enmeshes growth factors, cells and mineral particles. In this way, MPM overcomes the drawbacks of PRF and PRP, as it possess an osteoconductive potential where the addition of the bony substitute results in a bone graft that is more malleable, stable with enhanced resistance to chewing forced and maintenance of the created volume. Fibrin fibers are reported to resist stretching more than five times its length without breackage.
MPM combines the best of both worlds; its mineral phase qualifies it as an osteoconductive scaffold for bone formation while its platelet concentrate phase grants it an osteoinductive property by the slow release of growth factors.
Till today, the used of particles for the bone grafting is recommended for minor defects, because the particles are not stable and it is hard to keep it in place under the chewing forces and movements. The Mineralized Plasmatic Matrix solved this problem, and open a new age for the use of particles grafting, because by using the fibrin network, it link all the particles together and offers a very good stability for the graft.