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Abstract Summary The tear film represents the first barrier of the eye against environmental harmful agents. It is critical for good vision and eye health as it protects the ocular surface with moisture, helps transport waste away from the ocular surface, and provides a smooth optical surface for visual function. Tear film stability and integrity can be affected by several local and systemic diseases. Diabetes Mellitus is one of the most common systemic diseases that has a clinical association with dry eye and other ocular surface problems. This study was performed to compare the tear film in normal population and diabetic patients of the same age group by using AS-OCT (OPTovue 100) and correlate the results with TBUT. We found that all tear function parameters, including TBUT, TMH, TMD and TMA (measured by AS-OCT) were lower in the diabetic group, and these abnormalities were related to poor metabolic control. |