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العنوان
Efficacy of adding calcitonin to methylprednisolone in erector spinae plane block for thoracic cancer pain management /
المؤلف
Kamel, Esraa Yosri Lotfi.
هيئة الاعداد
باحث / إسراء يسرى لطفى كامل
مشرف / مدحت مخائيل مسيحه
مشرف / مصطفى سيد أحمد محمد العوضي
مناقش / هناء محمود حسين البنداري
مناقش / أيمن عبدالمقصود يوسف
الموضوع
Chest - Cancer. Chest - Cancer - Treatment. Chest - Surgery.
تاريخ النشر
2021.
عدد الصفحات
online resource (91 pages) :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
التخدير و علاج الألم
تاريخ الإجازة
1/1/2021
مكان الإجازة
جامعة المنصورة - كلية الطب - قسم التخدير والعناية المركزة الجراحية
الفهرس
Only 14 pages are availabe for public view

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from 120

Abstract

Introduction : Pain is a common symptom in cancer patients at all stages of their illness, and it is frequently undertreated. Pain is experienced by 59 %of all cancer patients, 64 %of those with advanced disease, and 33 % of those who have received curative care. Aim of this study: to compare the effect of adding calcitonin to methylprednisolone versus methylprednisolone alone to local anesthetic in erector spinae plane block for patient suffering from thoracic cancer pain. Patients and methods: Patients aged 30-70 years old from both sexes with a history of chronic thoracic cancer pain ≥ 4 on a visual analogue scale (VAS) of 0–10 and chronic pain for at least 3 months prior to study entry were included in this study. Methods: a prospective randomized double blind controlled study was conducted in OCMU from November 2019 until November 2020. Patients were interviewed and written informed consents were obtained from 30 patients presented with thoracic cancer pain.were randomly allocated into 2 equal groups : group I (control group) (methylprednisolone group) (n=15) received 40 mg methylprednisolone with 10 mL lidocaine 2% using ultrasound at the site of pain. group II (calcitonin group) (n=15) received 40 mg methylprednisolone added to 10 mL of 2% lidocaine plus 50 international units (IU) of calcitonin. Results : calcitonin group showed statistically significant lower VAS values after 1, 2 and 3 months,lower tramadol requirements after one and two months as compared to methylprednisolone group and more prolonged request of resque analgesia as compared to methylprednisolone group. Conclusion : Patients received calcitonin added to methylprednisolone and local anesthetics had significant reduction in pain scores, more prolonged duration of pain relief, less rescue analgesia (tramadol) consumed and was more satisfied with the treatment modality as compared to methylprednisolone and local anesthetics treated patients in a 3 months follow up periods.