الفهرس 
IntroductionOnly 14 pages are availabe for public view
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Abstract
This thesis was conducted in Alexandria University Hospitals on 30 patients harboring intraventricular tumors. The study aims at evaluation of predictive and prognostic factors responsible for choice of surgical approaches to lateral ventricular lesions and their impact on surgical outcome. The patients’ ages varied 1-55 years old and included 15 males and 15 females. All patients presented with headaches in addition to other symptoms including seizures and visual deficits. Large and medium sized tumors were detected in 73.3% of the patients. Preoperative hydrocephalus was diagnosed in 63.3% of the cases but was not statistically correlated to the need of permanent cerebrospinal fluid shunts. Transcortical approaches were utilized in 83.3% of the cases and were not associated with increased risk of postoperative seizures. Transcallosal approaches were utilized in 16.7% of the cases and were mainly utilized in small sized intraventricular tumors. External ventricular drains were inserted at the end of tumor excision surgeries in 16 (53.3%) cases among which 10 cases need permanent subsequent cerebrospinal fluid shunting. Postoperative hydrocephalus correlated statistically with the need of permanent cerebrospinal fluid shunting. Gross total resection was achieved in 86.6% of the cases. Subependymal giant cell astrocytoma and central neurocytoma constituted 50% of the cases. All postoperative complications were transient and reversible within 3 months. No perioperative mortalities were recorded in this study. 93.3% of the cases showed excellent clinical outcomes at 3, 6, and 9 months postoperatively. Transcortical and transcallosal approaches to intraventricular tumors are considered safe corridors that provide good clinical outcomes and tumor resection rates provided meticulous surgical planning is performed.