الفهرس 
Introduction and Aim of WorkOnly 14 pages are availabe for public view
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Abstract
Hepatitis B virus (HBV) afflicts more than 300 million people universal and is a main cause of liver and liver disease (Liang, 2009). It is a member of the Hepadnaviridae family, a small DNA virus with unique characteristics similar to retroviruses (Yan et al., 1996) It isreplicates by RNA intermediate and can integrate into the host genome. The greatest incidence areas for HBV infection (>8%) are in African, Western Pacific and Asian countries where the virus is acquired through many ways e.g. prenatal transmission from the chronically infected mother or through infection in early childhood, surgical equipment’s, and saliva (Park et al., 2011). By using a sterile plastic syringe for each subjects, 5 ml of venous blood is withdrawn and divided as follow 1ml is put in a tube Containing EDTA for CBC; 2ml is put in a plain tube then allowed to centrifuge to separate serum for estimation of liver function, kidney fuction, LDH, HBx Protein (ELISA). In addition two ml is put in a heparin tube for virologestimation and quantitative HBV DNA by PCR Viruses are very entity germs that are made of genetic material inside of a protein coating. Most viruses could cause familiar infectious diseases. They invade normal cells in order to multiply and produce other viruses. Different viruses attack certain cells in the human body such as the liver, respiratory system, blood, or lymph node. The most common was HBV. Moreover, about 300 million cases were chronically infected with HBV. Most research is dealt with the impact of these viruses as a risk factor and causative agents of cancer especially hepatocellular carcinoma (HCC) and lymphoma.