الفهرس | Only 14 pages are availabe for public view |
Abstract DTI is a recent technique which permits for non-invasive quantification of WM microstructural changes in epilepsy patients. Tractography is now a frequently used technique to study the anatomy of the human white matter. This technique helps to visualize trajectories of particular bundles of WM fibers and has the ability to conduct quantitative assessment of individual tracts properties. This makes it possible for us to determine the effect of diseases on particular WM tracts. The objective of our study was to decide if quantitative DTI can display abnormalities in various WM tracts in pediatric epilepsy patients. Our findings showed reduced FA values associated with increased diffusivity measures in a wide range of WM fiber bundles in epilepsy patients. FA quantifies the desired direction while MD quantifies the mean of water diffusion extension in white matter. The detailed qualitative and quantitative information about WM microstructural organization and integrity in children with brain malformations can be also assessed by DTI and FT. So, these findings may be significant for ongoing evaluation and protocols of management of patients with pediatric epilepsy. |