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العنوان
Assessment Of Immunological Changes Disorders In Cases Of Thyroid Eye Disease By Impression Cytology /
المؤلف
Mahmoud, Eslam Magdy.
هيئة الاعداد
باحث / اسلام مجدى محمود
مشرف / سعـــد محمـــد رشـــاد
مشرف / محمود احمد السمكرى
مشرف / رضوى محمد نبيل
تاريخ النشر
2020.
عدد الصفحات
98 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
طب العيون
تاريخ الإجازة
23/4/2020
مكان الإجازة
جامعة عين شمس - كلية الطب - قسم وجراحة العيون
الفهرس
Only 14 pages are availabe for public view

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from 98

Abstract

Impression cytology is a technique which permits the retrieval of the outermost layer of ocular surface cells via the use of various types of filters, it is a minimally invasive method of evaluating human conjunctival epithelial cell morphology which could be utilized in the diagnosis of ocular surface diseases, such as thyroid eye disease.
Our thesis was designed as a prospective cross sectional study to understand the effects of TED on ocular surface among TED patients in comparison to healthy persons by using impression cytology.
A cross sectional observational study designed to analyze data of 40 eyes arranged into 2 groups: (group 1: thyroid eye disease, group 2: control) 20 eyes in each group. The study was performed in the time interval between May 2019 and December 2019.
Our study showed that patients with TED group had ocular surface changes revealed as squamous metaplasia with cell polymorphism, goblet cells deficiency ,epithelial keratinization and inflammatory cells infiltration, while control group did not showed these changes, the degree of these changes differ according to the stages reveled by impression cytology we did, and by using classification of Tseng (1985) .
Results of our study showed that TED group hertel exophtalmometer measurement had an average of 22.6 ± 0.98 mm while control group showed an average of 17.50 ± 0.89 , (65 %) of TED group showed stage 2 in impression cytology technique while most of control group (80%) showed stage 0 , we also used this technique to discover the presence of inflammation and degree of it and we found that 80% of this group showed moderate degree of inflammation while impression cytology results of the control group showed that 80% of them were almost nil degree of inflammation.