الفهرس 
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Abstract
Introduction: Immunosuppressive drugs are frequently used in clinical medicine for an assortment of disorders, but a paucity of information is available about their effect on the pulp healing, so further investigations are needed. The current study evaluated and compared the effect of different immunosuppressive drug regimens on the healing capacity of mechanically exposed dogs’ dental pulps capped with four different capping materials. Methods: Eight healthy male dogs, aged 2-3 years were used. These dogs were randomly assigned into four equal groups, 2 dogs each,: group 1 representing control group where no drugs were received; group 2 given Prednisone (Pred); group 3 given a combination of Pred and Cyclosporine A (CsA); and group 4 given triple dose including Pred, CsA, and Mycophenolate mofetil (MMF) for 45 days before starting the operative procedures and until the dogs were euthanized. Class V cavities were prepared on the labial surfaces of 16 teeth in each dog. In each cavity, the pulp was exposed and capped with either mineral trioxide aggregate (MTA), biodentine (tricalcium silicate-based material), TheraCal LC (light-curable resin-modified tricalcium silicate-based material), or Dycal (Calcium hydroxide based cement) (n=8 for each subgroup). Then, all cavities were sealed with IRM (reinforced zinc oxide-eugenol cement). The pulpal tissue responses to the capping material were assessed 65 days postoperatively.