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العنوان
Effect of Magnesium Sulphate on Neuromuscular Recovery characteristics of Rocuronium Using Sugammadex Reversal /
المؤلف
Mewafy, Mahmoud Ahmed Mahmoud.
هيئة الاعداد
باحث / محمود احمد محمود محمد موافى
مشرف / محمد عماد الدين عبد الغفار
مشرف / فاطمة محمد خميس
مشرف / عماد الدين احمد
الموضوع
Anesthesia.
تاريخ النشر
2020.
عدد الصفحات
82 P. :
اللغة
الإنجليزية
الدرجة
الدكتوراه
التخصص
التخدير و علاج الألم
تاريخ الإجازة
1/1/2020
مكان الإجازة
جامعة قناة السويس - كلية الطب - Anesthesia
الفهرس
Only 14 pages are availabe for public view

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from 82

Abstract

The use of Magnesium Sulphate during anesthesia has increased because of its benefits to the patients with various clinical conditions, such as preeclampsia , cardiac arrhythmias , acute bronchospasm and postoperative pain (1-3).
Magnesium is necessary for the presynaptic release of acetylcholine from nerve endings (5)
Interactions between (MgSO4) and neuromuscular blockers alter pharmacodynamic variables and may predispose patients to postoperative respiratory complications (6).
Magnesium significantly decreases onset time and increases recovery time, and recurarisation may occur when Magnesium Sulphate was used following recovery from neuromuscular blockade (6-8).
The aim of the study was to assess the efficacy of Sugammadex in reversing moderate Rocuronium-induced neuromuscular blockade in patients pretreated with Magnesium Sulphate.
Following approval of Suez Canal University ethical committee, patient recruitment occurred during the pre-anesthetic visit.
During the preoperative visit, the techniques were explained to the patients including benefits and possible complications of the procedure and a written consent was taken.
The study was an interventional study including 40 patients that were divided randomly into two groups: Magnesium group with 20 patients and Control group (saline group) with 20 patients at Suez Canal University hospitals in Ismailia.