الفهرس | Only 14 pages are availabe for public view |
Abstract Summary Unnecessary delay in weaning from mechanical ventilation may lead to deleterious complications such as ventilator associated pneumonia, ventilator induced diaphragmatic atrophy, endotracheal obstruction and tracheal stenosis . Weaning failure is likely if the load on inspiratory muscles is excessive relative to their neuromuscular capacity. The diaphragm is a fundamental respiratory muscle whose dysfunction may be very common in patients undergoing mechanical ventilation. Timing is critical for proper weaning from mechanical ventilation as premature weaning may lead to increased cardiovascular, respiratory stress, Co2 retention and hypoxemia . Diaphragmatic ultrasonography (US) has emerged as a tool to predict weaning outcome from mechanical ventilation or extubation in the intensive care unit (ICU). Diaphragmatic amplitude during contraction help to diagnose diaphragmatic weakness and respiratory workload, while duration of inspiration during spontaneous breathing has direct impact on work performed by diaphragm. Diaphragmatic Excursion –time index is a product of diaphragm excursion multiplied by inspiratory time can be used to predict the out come of extubation. Our prospective randomized study aimed to assess accuracy of diaphragmatic excursion time index measured by ultrasound as a predictor of successful weaning from mechanical ventilation. |