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العنوان
Outcome of Vitamin D Supplementation Versus Progestin Therapy in Endometrial Hyperplasia Without Atypia /
المؤلف
Ebrahim, Nesma Ali.
هيئة الاعداد
باحث / ممدوح المهدي سعيد
مشرف / ايمان احمد كشك
مشرف / احمد محمد جادالله
مشرف / احمد محمد جادالله
الموضوع
Obstetrics and Gynecology.
تاريخ النشر
2020.
عدد الصفحات
106 P. ;
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
أمراض النساء والتوليد
تاريخ الإجازة
1/1/2020
مكان الإجازة
جامعة قناة السويس - كلية الطب - النسا و التوليد- مستشفيي بورسعيد العام
الفهرس
Only 14 pages are availabe for public view

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Abstract

Endometrial hyperplasia (EH) is defined as an increased ratio of endometrial glands to stroma greater than one to one.
Endometrial hyperplasia arises from the endometrial glands, and its incidence is highly associated with prolonged unopposed estrogen action explaining its response to progestins leading to its regression. Thus hormonal therapy has been used as an alternative treatment for a specific subset of patients where preservation of fertility is desired or if comorbidities exclude them from surgical intervention.
Experimental evidence has suggested a possible association between vitamin D and cancer risk. In studies of cancer cells and of tumors in mice, vitamin D has been found to have several activities that might slow or prevent the development of cancer, including promoting cellular differentiation, decreasing cancer cell growth, stimulating apoptosis, and reducing tumor blood vessel formation.